The cell Milopotam is located on the border between Iveron and Philotheou monasteries and belongs to the monastery of Great Lavra. On the way from the cell numerous water mills are to be met hence the name "Milopotam". The cell was founded by Athonite Athanasius in 972 year as a clinic for monks of Great Lavra.

In 1527 Milopotam was plundered and burnt down by Muslims and later re-established by Metropolitan Ternovsky Theofil. From 1899 till 1901 the Patriarch Ioakim III lived there before he became Ecumenical Patriarch.

Nowadays Milopotam is flourishing thanks to the monks living there. The katholikon of the cell is dedicated to Saint Martyr Euthimios. Milopotam is well known for its vineyard and vine of the same name.